What is SLU-PP-332?
SLU-PP-332 is a synthetic small molecule that functions as a potent but non-selective agonist of the estrogen-related receptor (ERR). It has gained significant attention in metabolic and mitochondrial function studies due to its potential exercise-mimetic properties.
Although this compound is still in the preclinical stages, and no human trials have been performed, it has exploded in popularity in health, fitness, and bio-hacking communities.

How does SLU-PP-332 work?
SLU-PP-332 is a potent estrogen receptor-related (ERR) agonist that mimics the health benefits of exercise. Its mechanism of action is based on the following:
- ERR Activation: It binds to and activates estrogen-related receptor proteins.
- Metabolic Cascade: Triggers a series of metabolic events throughout the body.
- Cellular Changes: Enhances energy expenditure, fatty acid oxidation, and insulin sensitivity.
- Mitochondrial Growth: Stimulates mitochondrial biogenesis, boosting cellular energy production
Potential benefits
Based on the results of animal studies and anecdotal reports by users, SLU-PP-332 may offer a range of potential benefits, including:
- Boosts Metabolism: Accelerates fat metabolism, mimicking endurance training and promoting faster energy expenditure.
- Increases Endurance: Mice treated with the drug ran 50% further, improving endurance without extra effort.
- Exercise-like benefits: Fat loss and muscle efficiency without the need for increased physical activity.
- Natural Metabolic Activation: Activates metabolic pathways to burn fat more efficiently, without affecting appetite.
Possible side effects
While specific side effects for this compound are not extensively documented, potential concerns may include:
- Unknown long-term effects
- Possible hormonal imbalances due to ERR activation
SLU-PP-332 recommended dosage
Because SLU-PP-332 lacks human trials and is currently not approved for human consumption, there are no official dosing guidelines. The following overview of daily dosages for SLU-PP-332 is therefore based on anecdotal evidence and user reports. It should not be interpreted as medical advice and is only intended for educational purposes:
- Low Doses (200–500 mcg/day): Some individuals start with 200 mcg in the morning and an additional 200 mcg before afternoon workouts. This regimen is noted for enhancing endurance and energy levels without significant side effects.
- Moderate Doses (500–1,000 mcg/day): Others increase to 500 mcg twice daily, observing consistent fat loss and elevated body temperature. However, some report sleep disturbances at these levels.
- High Doses (1,000–2,000 mcg/day): A subset of users experiment with doses up to 2,000 mcg daily, often split between morning and evening. These individuals often report pronounced effects on fat metabolism and energy but also caution about potential overstimulation.
It is recommended to start with a low dose and gradually increase the dose to assess tolerance. Consulting a healthcare professional before use is recommended to ensure safety and effectiveness.
Legal status
SLU-PP-332 has not been approved by the FDA or EMA for human consumption or therapeutic use. It can therefore not be legally prescribed or sold as a supplement.
At this moment, it is not yet on the WADA list of prohibited substances.
You can buy SLU-PP-332 from HQSARMS for research purposes.
Product specifications
| Application | Estrogen related receptors agonist |
| Form | Liquid |
| Concentration | 1000 mcg per ml |
| Composition | 99.9% PEG-400, 0.1% SLU-PP-332 |
| Purity | >99% |
| Storage | Room temperature |
| Storage life | 2 years |
| CAS | 303760-60-3 |
| Molecular Weight | 290.32 g/mol |
| Chemical Formula | C₁₈H₁₄N₂O₂ |
| IUPAC Name | 4-hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino]benzamide |
| Synonyms | SLUPP332, SLU PP 332, CHEMBL4208749, SCHEMBL12937827, BDBM50455424, STK082756 |
Frequently asked questions
Is SLU-PP-332 a peptide?
No. It is a chemically synthesized, non-peptidic compound designed for oral bioavailability. Peptides are chains of amino acids linked by peptide bonds. SLU-PP-332 does not have that structure.
Is SLU-PP-332 a SARM?
No. It is not a SARM. SARMs (Selective Androgen Receptor Modulators) act specifically on the androgen receptor. SLU-PP-332 is a synthetic agonist of estrogen-related receptors (ERRα, ERRβ, ERRγ). It has no activity at the androgen receptor.
Is SLU-PP-332 orally active?
Yes. Based on available research, it has an oral bioavailability of 45%.
What is the common dosage for SLU-PP-332?
The most common dose for SLU-PP-332 is between 250 mcg and 1000 mcg per day.
Where to buy SLU-PP-332 online?
You can buy SLU-PP-332 online at HQSARMS. Our liquid has a potency of 1000 mcg/ml or 1 mg/ml, which is higher than what is offered by almost every competitor on the market.








