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Ibutamoren - Everything you need to know

All you need to know about MK-677

What is MK-677?

MK-677, also known as Ibutamoren, is a growth hormone secretagogue that is highly popular among athletes and bodybuilders. It is one of those compounds often referred to as a SARM. But it actually isn’t a Selective Androgen Receptor Modulator at all.

Mk-677 Ibutamoren molecule

Ibutamoren is actually a selective agonist of the growth hormone secretagogue. It mimics the action of ghrelin (the hormone that regulates appetite and the distribution and rate of use of energy) in the stomach, raising growth hormone and IGF-1 levels, but does not affect cortisol levels. It is the only orally active compound that stimulates the secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1).

Other growth hormone secretagogues are mostly peptides, such as GHRP-2, GHRP-6, Hexarelin, and others. Most of these substances increase cortisol levels. The same is not true for MK 677, which is one of the reasons why this compound is unique.

How does MK 677 work?

Human studies have shown MK 677, also known as Ibutamoren and Nutrobal to increase both muscle mass and bone mineral density. Dosed at 25mg daily, Ibutamoren increases IGF-1 levels by 60% in 6 weeks in humans. A 72% increase in IGF-1 levels was seen after 12 months.

Ibutamoren is frequently used as an anabolic substance, to increase lean body mass. It works by mimicking the ghrelin receptor, which is not something that many compounds are capable of.

MK 677 increases the secretion of Growth Hormone (GH) as well as Insulin-Like Growth factor (IGF-1). Both of these play a large role in muscle growth, recovery, and cell regeneration.

Body composition with MK-677

What are the benefits of MK 677?

By elevating the levels of GH (growth hormone) and IGF-1 (insulin-like growth factor 1), MK677 offers a myriad of remarkable health benefits, which include:

  • Reducing muscle wasting
  • Increasing bone density
  • Improving quality of sleep
  • Improving recovery

The primary benefit of MK 677 is that it increases both GH and IGF-1 levels in the body.

But, what does it mean to have increased levels of these hormones?

Both Growth hormone and Insulin-Like Growth Factor-1 aid muscle growth, recovery, strength, and performance. Research indicates a potential benefit of MK677 in catabolic conditions treatment.

Reduces muscle wasting

MK 677 seems to reduce muscle wasting that can be caused by a decline in protein intake within a persons diet. One study on healthy, young individuals, focused on the possibility to reverse protein-induced catabolism. The result was positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.

Increase bone density

Several studies have shown that the long-term use of MK-677 can have enormous results in increasing bone mineral density. Bone loss is a common problem in obese individuals, aging adults, and women with menopause. For them, this can have detrimental health problems due to low bone mineral density, and MK-677 has proven to be an effective treatment for many of them.

In 24 healthy obese male volunteers, ibutamoren increased bone turnover.

Another study was performed on 187 elderly adults (65 years or older). Ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies.

In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.

Ibutamoren improves sleep quality

Growth hormone plays an important role in the quality of sleep. Because MK-677 Ibutamoren increases growth hormone, it improves sleep quality by prolonging the duration of REM sleep. This is the sleep stage where most recovery is taking place. This effect is shown in numerous scientific studies and in anecdotal evidence by many users.

Apart from scientific studies, there are many user reports that mention an improved sleep quality.

MK677 for faster recovery

An increase in growth hormone levels has many positive effects. For instance, it provides faster recovery by improving tissue regeneration. This results in better healing of tendons as well as skin and nails.

Possible nootropic effects

Since MK-677 binds to the same receptors as ghrelin, it is likely to have similar positive effects on cognitive functions as ghrelin.

It is, however, important to point out that there have yet to be any scientific studies that prove this assumption. We are aware of the important role that REM sleep plays in cognitive functions. Additionally, the impact of IGF-1 on cognitive functions is well-established.

Where to buy MK-677?

It is important to buy Ibutamoren from a trusted source such as HQSARMS.

Side effects

Although the use of Ibutamoren is generally well-tolerated, it is worth noting that some individuals may experience minor side effects. These side effects are usually not serious and tend to resolve on their own. Some of the most commonly reported side effects of MK-677 include:

An increase in appetite

Ibutamoren mimics the effects of Ghrelin. As a result, MK-667 increases appetite significantly, just like ghrelin. This effect is strongest during the first couple of weeks.

Mild lower extremity edema

MK-677 can cause mild lower extremity edema, which basically means that it increases water retention in feet and hands. This effect is most apparent during the first few weeks.

Increase in insuline sensivity

Because Ibutamoren increases IGF-1 (Insulin-like growth factor 1), it can also increase blood sugar, which is a risk for people with diabetes or high insulin sensitivity.

Stacking Ibutamoren

MK-677 is a powerful compound that provides excellent results when used solo. To achieve even better results, it is often stacked with anabolic steroids or with SARMS.

Some popular examples:

For bulking purposes you can choose a stack MK-677 + LGD-4033 + RAD-140

MK-677 questions

Is MK-677 safe?

During clinical trials MK-677 was well tolerated by the subjects. No serious adverse effects where observed in any of the patients. There are no studies on the long-term side effects of MK-677.

Does MK-677 require a PCT?

MK 677 does not require a Post Cycle Therapy (PCT) because it does not suppress the levels of testosterone in the body.

Is MK 677 legal?

MK 677, also known as Ibutamoren, is currently classified as a research drug and is legal for purchase in almost all countries of the world, except Australia. It is similar in legal status to SARMs and is widely available for research purposes.

Does MK 677 suppress testosterone?

No, Ibutamoren does not cause any suppression in testosterone levels because it doesn’t target androgen receptors. Studies confirm that MK-677 does not suppress testosterone levels.

What is the half-life of MK677?

Ibutamoren has a half-life of approximately 24 hours, meaning that its effects remain active in the body for a considerable amount of time. As a result, it is typically taken only once per day. A standard 25mg daily dosage is typically recommended for users looking to experience the benefits of Ibutamoren.

What is the proper dosage for MK 667?

The most common dose for Ibutamoren is 25mg per day. Using a higher dosage does not seem to be more effective.

Is MK 677 a SARM?

No. SARMs are compounds that target the androgen receptors, in a somewhat similar way that anabolic steroids do. MK 677 increases growth hormone levels.

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